A Grammy-winning singer and his family have revealed the surprising early symptoms of his brain cancer .
Michael Bolton, who was diagnosed in December 2023 with glioblastoma — the most aggressive and fastest-growing form of brain cancer — first exhibited signs that something was amiss the month prior, according to his daughters.
During a family night at the bowling alley, Bolton, 72, bowled out of turn several times, they told People during a recent interview.
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On the same evening, the vocalist had also tumbled out of his seat, an occurrence described as "highly uncommon" by Taryn, who is 45 years old, to the publication.

"He’s super athletic, and he doesn’t drink," she said. "So he fell, and we were like, ‘What just happened?’"
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"That was when we were like, ‘Something’s wrong with his brain ."
Reflecting back, Bolton’s daughters acknowledge "a multitude of things" they overlooked at the time.
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In an earlier part of that autumn, the Grammy-winning artist had difficulty maintaining his balance and felt nauseous during a performance at a charitable function.
His daughters believed that the unusual symptoms were because they hadn't gotten enough rest. excess stress , they said.
Taryn remembered telling People, "He had been continuously working during that entire period."
"Traveling, doing shows, doing all of these things. We were like, he’s getting older, he’s tired, he’s stressed out. All of these things we sort of explained in a way, one by one."
Following the strange symptoms while bowling, Bolton began experiencing headaches, his daughters shared.
The subsequent Monday, he underwent an MRI which revealed a brain tumor , which was removed surgically and found to be glioblastoma.
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Although uncommon, glioblastoma tends to impact individuals regardless of their age and is recognized for its rapid and aggressive progression, as stated by Michael Canney Ph.D., the chief scientific officer at Carthera—a healthcare technology firm based in Colorado that focuses on developing treatments in this area. medical devices to address serious neurological conditions.
"While the exact origin of glioblastoma remains unclear, the condition starts when genetic alterations in brain cells lead to uncontrolled growth," explained Canney, who wasn't part of Bolton’s treatment team, to Fox News Digital.

These malignant cells quickly infiltrate nearby brain tissue, rendering the tumor particularly aggressive and difficult to address.
Canney verified that the symptoms Bolton had — disorientation, abrupt collapses and severe headaches —are consistent with symptoms of glioblastoma.
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Additional warning signs might consist of nausea, memory impairment, alterations in personality, and challenges with speech. vision changes ," he added.
Although the signs of glioblastoma aren’t exclusive to this condition, should you or someone close to you encounter unexpected alterations in conduct, cognitive function, or physical coordination, it’s crucial to consult with a healthcare provider.

After surgery, Bolton completed radiation and chemotherapy , which have so far kept cancer at bay, the report noted.
He receives ongoing MRIs every two months to ensure that he is still clear of tumors.
Glioblastoma ranks as one of the most lethal forms of cancer, typically allowing patients only about a year of additional life following their diagnosis. The likelihood of surviving at least five years post-diagnosis is below 5%.
"It is truly among the most tragic diseases," Canney said.
One reason why glioblastoma is so serious is because it is resistant to therapy, as explained by the specialist.
Encircling your brain, there exists a built-in safeguard known as the blood-brain barrier. blood-brain barrier ," he told Fox News Digital.
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"While this barrier keeps the brain safe from toxins and other harmful substances, it also blocks the life-saving chemotherapy drugs used in treating most cancers."
In some cases, including Bolton’s, glioblastoma treatment can begin with surgery Canney mentioned that removing the tumor is possible as long as it hasn't deeply infiltrated the brain.

Other treatment options include radiation and chemotherapy, which can "modestly extend survival," he noted.
"Although current treatment options are limited, a number of clinical trials are underway that give us an immense sense of hope," Canney said, pointing out a new form of ultrasound-based technology that is showing promise.
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"If approved, this technology will enable doctors to safely and temporarily open the blood-brain barrier for the first time ever — allowing a greater number of potentially more effective chemotherapy drugs into the brain."
Original article source: Michael Bolton had strange symptoms before brain cancer diagnosis: ‘Something’s wrong’
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